Space demons! and other universal interlopers

At the edge of the solar system, impossibly, They are here, pouring through a hole in reality...

Humans rally their forces and wonder: can we beat them? Is this the end? And importantly, why are they here???

1. Counter-humans from an inverse-universe determined to conquer our space.
2. Insectoid menace plundering precious resources: humans!
3. Blurred-edge fractal-flowers, AIs that want to be the only consciousness.
4. Conceptual bubble-beings; they feed off maths and want more equations to devour.
5. Swarm of nano-constructors; absorbing comet ice and space dust, and looking at that hot glowing ball of gas in the distance with hunger.
6. Spike-ships colonised by ant-people parasite-pilots are searching for something good to drink: humans!
7. Matriarchal anti-entropic space-pirates looking for a new star to turn into pure computronium.
8. Macro-scale germ-hive searching for the ultimate infectees: whales! (or, if whales extinct: humans!)
9. Cat-headed demons of the negaverse; searching for a great big saucer of milk.
10. Aesthovores, art-eating twelve-legged spiders from dream-space; attracted by Earth culture and looking to farm artists from the closest source: humans!

Whoever They are, humans can't win. We can probably hide and survive in the ruins though...

(From notes for an old Into The Oort supplement idea I had. The canon Oort setting had no aliens, just leftover tech from older human communities, but commenters seemed interested in space demons and Other Menaces. The table also probably owes a debt to To The Stars, the shared game universe that I, David McGrogan, Patrick Stuart and others played games in years ago.)